Abstract: By analyzing and comparing the space conception of geography subjects,this paper discusses the space conception of the geographic information system,and points out that the space mathematics basis of the geographic information system has been the mathematics definition of the space conception of GIS.This paper has opened out and demonstrated the space mathematics basis of GIS.Hereby,it discusses a current hot topic-"the seamless space database" technology,and points out that what is called"seamless" is not only formal"the seamless visualization",but"the seamless measurement","the seamless space analysis" and"the seamless standardization integration".Finally,it disserts some of topics about space analysis theory and technology of"the seamless space database",space data expression,NGDF and technology route,movement geometry on Earth,environment and other problems.