Abstract: Using the observation data of GPS sites in southern Qinghai-Tibet plateau in recent 10 years (2004-2014) and combing with the observation data inversion of the GRACE period regional hydrological load changes caused by the vertical displacement, it can be found by GPS and GRACE that there is a vertical displacement time series in a certain correlation. The correlation coefficient of most sites is around 0.7; especially the site of Himalayan orogenic belt, the correlation is higher than others. Most sites, such as CHLM and KKN4, the fitting cycle amplitude and phase are in consistent. Defining Ratio_WRMS to characterize of GRACE to correct the effectiveness of the GPS vertical hydrological load, the value closing to 1 indicates that GPS and GRACE data have a greater consistency; The study showed that the different areas of GPS sites R_WRMS have obvious differences:maximum and minimum value are respectively 0.96 (TPLJ) and 0.24 (XZGE), while the average is 0.64. This is associated with the south Tibetan region of the complexity of the vertical movement, there are many factors (tectonic movement, GIA, the non-tidal atmosphere and ocean, Seasonal Hydrological Load, the tides, etc.) work together.This article research results to further study the south Tibetan region of tectonic movement has important reference value.