Abstract: 3D point pattern of cluster analysis is presented based on 3D Voronoi. 3D Voronoi cell is used to represent the spatial region that the spatial point effects. Through a quantitative description of the spatial parameters about 3D Voronoi cell there exists the potential to distinguish the weight and effective quantity of each point in the 3D space. Spatial neighborhood relationship among points is extracted according to 3D Voronoi cells to delimit the candidate points that will be clustered. The method illustrates segmentation and cluster distribution of 3D points based on the underlying density and spatial relationships, and actual analysis is imposed on the point cloud of 3D rabbit (Bunny). The ability to make quantitative description of each 3D Voronoi cell gives insights into spatial controls and cluster process on 3D points.