Abstract: A new method of regional ionosphere delays' calibration based on uncombined precise point positioning(PPP) is proposed in this paper,and the accuracy is assessed by interpolating the calibrated delays at a user station with single frequency simulated kinematic PPP implementation.The results show that the accuracy of interpolation is better than 1 dm and less affected by the ionosphere activity;the positioning accuracy of single frequency simulated kinematic PPP are 4~5 cm for panel and better than 1 dm for vertical respectively.Comparatively,two reference solutions are also obtained in single frequency simulated kinematic PPP mode,with eliminating ionosphere delays either by forming semi-combination observations or interpolated values from global ionosphere maps(GIM),the positioning accuracy of both cases are approximately 4~7 dm and 1 m for the panel and vertical respectively.