Abstract: This paper briefly describes the structure of the nailflod microcirculation quantitative analysis system, the principle of its operation and the methods of processing. Given an image of the nailfold microcirculation, after processing it to a certain degree, this system can be used to measure some pertinent parameters quantitatively. Then, from the viewpoint of the medicine, these parameters are analyzed and calculated so as to provide strong evidences to diagnosis, treatment and precaution of diseases.