Abstract: This paper makes an attempt to study image segmentation with the technology of chemical reaction optimization.Firstly the paper introduces the relationship between CRO and image segmentation,then it analyses the new method of image segmentation in detail.On this basis,it expatiates on the operational process of this new method concretely.Furthermore,the paper validates the accuracy of our analysis on features of the new method through a segmentation experiment of three aerial photographs,and gets some useful conclusions at last.