Abstract: Atmospheric precipitable water vapor is an important element of the meteorological and meteorological disaster forecast. Using the ECMWF data for regional meteorological research is one of the current research focuses.For the problem caused by the low spatial resolution of the ECMWF data in studying the small regional meteorologicala，we studied the ECMWF water vapor interpolation idea with the Stretched Boundary Layer，and we established the model and realized it.This model can be used to interpolate the ECMWF water vapor，surface pressure and surface temperature. We can obtain the results in any density based on region DEM resolution. The model is tested with the UPS water vapor observations and surface meteorological data from the UPS-IPW network of the U.S.The results show that the model can improve the accuracy greatly on the ECMWF water vapor，surface pressure and surface temperature compared to the raw ECMWF data.