Abstract: With the emergence and continuous development of Geographic Information Systems, Geographic Information Science proposed in the nineties of last century has gradually become an emerging discipline between Geography, Information Science, Surveying and Mapping. Adhering to the basic judgment that Geographic Information Science is still an open knowledge system, this paper starts from the basic discipline characteristics of Geography and Information Science, the superior disciplines of Geographic Information Science, focuses on its basic and scientific attributes, and discusses the basic discipline paradigm for the further development of Geographic Information Science, so as to provide a potential development path for the continuous improvement of the knowledge system of Geographic Information Science and the strengthening of the scientific, basic and systematic nature of Geographic Information Science.