Abstract: The environment of the lunar surface is quite complex and under such complicated lunar environment, how to effectively get a reasonable, safe, and scientific valuable exploration area is extremely important for the lunar exploration program. To solve this problem, firstly, based on the available lunar exploration data and some research work about the landing site selection, this approach investigated the lunar environmental indicators that might influence the exploration work, after that, an interactive GIS prototype system for exploration area selection was designed and developed, and based on the system the environmental indicators were used to construct exploration area selection model dynamically, with which the right exploration area could be calculated and visualized automatically. This system was successfully implemented in the scientific exploration selection work for the Chang'E 3 lunar rover, and the exploration selection result shows that it is good for the lunar exploration.